Other reports have described cases of TBE in children melanoma with only vague fever symptoms [15],

Summary in English
Tick-borne melanoma encephalitis (TBE) is a vector-borne viral disease that has increased in incidence and prevalence in recent years, both in Sweden and several countries in Central and Eastern Europe [1-3]. Since it is less generous with sampling for TBE in non-endemic areas, the actual incidence and prevalence have been underestimated [3]. TBE causes severe meningoencephalitis, which can lead to chronic neurological and cognitive disability.
There is a vaccine that provides good, but relatively short-acting protection where after primary vaccination melanoma consisting of three doses must give booster doses after 3 years and then every 5 years. Vaccination breakthrough occurs, however. Previously it has been determined that children under 7 years rarely get sick, and if they fall ill, they get a milder or asymptomatic infection [4]. The recommendation was therefore prior to vaccination were less keen for children aged up to 7 years.
In recent years, however, studies have reported that children become ill and can be permanently disabled, including difficulty in concentration [5, 6]. The recommendation has been changed a few times regarding the age at which vaccination against TBE should be started until 2012 was recommended vaccinations melanoma from 3 years of age [7]. The data available in the literature in this area, however no safe support for a precise age limit and therefore reads rather its most recent recommendation [8]: "TBE vaccine for children can be given from the age of 1 year and generally gives good protection against melanoma disease in children. Aim and method
This literature review aims to summarize melanoma the studies done in this area and, in combination with national surveillance data discuss a reasonable age to begin TBE vaccination in children in endemic areas. The following issues are highlighted: How common is TBE with residual neurological disabilities in children under 7 years in endemic areas? Which antibody response and protection achieved in children under 7 years after vaccination against TBE? Are there grounds to recommend vaccination against TBE children from just 3 years of age in endemic melanoma areas? melanoma
A review of scientific articles on TBE in children has been made, through a search in PubMed. Mainly used the keywords "TBE", "Children," "outcome", "vaccination", "vaccine failure". Statistics derived in notifications to the Infectious Diseases Institute also presented. Difficulty increases with higher age
TBE is a neurotropic, tick-borne flaviviruses in humans produces a clinical picture that varies from asymptomatic infection to meningitis, meningoencephalitis or meningoencefalomyelit, which is the most severe form [9]. Persistent neurologic sequelae occur in 27-58 percent of adults TBE patients, mainly in the form of paresis and ataxia and cognitive and neuropsychiatric impairments such as memory problems and concentration problems [9]. It is well described in the literature that the severity of both the acute phase and the level of residual disability increases with age [9-11]. Mortality is reported to 0.5-1.5 percent, but deaths in children and young adults are rare [12]. Clinical picture of children
That the disease is usually milder and less common in children does not mean that there are no serious disease melanoma and sequelae even in younger children. melanoma A number of studies have focused on TBE infections in children.
Retrospectively studied melanoma 116 Austrian children who fell ill in TBE during 1981-2005 [13]. Of these, about 80 percent meningitis and 20 percent meningoencephalitis. Several cases requiring intensive care, including four of the 11 youngest in the age group 0-3 years. Only two (1.7 percent) of the 116 children were found to have sequelae at clinical follow-up after 6 months. These were serious handicaps: melanoma a 7 year old with epilepsy and a 5 year old with left-sided hemiparesis.
Another retrospective study from Slovenia during 1951-2000 included 371 children under the age of 15 with TBE [14]. Children under 15 accounted for 24 percent of all TBE cases in the region during the period, but only 29 cases (1.8 percent) occurred in children under 6 years of age. Meningitis occurred in 62 percent and encephalitis in 37 percent of the entire group of children. Encephalitis was more common in older children. No neurological sequelae were reported, and the authors concluded that TBE is a mild disease with benign course in children.
The same assessment was made after comparing the clinical course of 20 children and 80 adults with TBE, also in Slovenia [10]. Even in adults, neurological sequelae relatively melanoma rarely in this study; only 2 of 80 had residual paresis.
Other reports have described cases of TBE in children melanoma with only vague fever symptoms [15], but severe forms of residual paresis also occur [16] as well as a number of case reports of severe encephalitis even in young children and infants [17].
Common to these previous studies is that they are mainly performed retrospectively through medical record review, with the exception of [10], and they said,