Friday, September 27, 2013

This study has found a correlation between elevated levels of C-reactive protein and macular edema


Diabetic retinopathy is the 1st cause of blindness in people of working age in developed countries. In most cases, vision loss is attributable to the diabetic macular edema. It is well known that poorly controlled diabetes and elevated levels of serum lipids carry a higher color blind test risk of developing diabetic macular edema. In addition, several studies have suggested that some degree of inflammation may play a role in the pathogenesis of diabetic retinopathy. For this reason it has been tried to find a correlation color blind test between different biomarkers of inflammation such as C-reactive protein, intercellular adhesion molecule 1, the vascular cell adhesion molecule 1 and the receptor of tumor necrosis factor alpha. The results have been conflicting studies, but had never performed a prospective study to this end.
Recently, the Diabetes color blind test Control and Complications Trial (DCCT) conducted color blind test a prospective, randomized, controlled, multicenter study (ie, with the highest level of evidence) from which other reliable conclusions can be drawn (JAMA Ophthalmol, 2013).
This study has found a correlation between elevated levels of C-reactive protein and macular edema with a relative color blind test risk of 1.83 from elevated levels of C-reactive protein to low levels of the same. Econtraron also a correlation between elevated levels of C-reactive protein and intercellular adhesion molecule 1 with the appearance of lipid exudates. color blind test There was no correlation of other markers with macular edema.
Protein C is an "acute phase reactant" whose levels color blind test increase when there is any inflammation in our body. Most people have plasma CRP less than 1 mg / L. Small elevations of the same are not detectable by conventional techniques and for this reason has developed the technique of C-reactive protein. This technique is used in cardiology for the risk of myocardial infarction color blind test and, as I have said on another post, you may also be useful to know the risk of severe forms of macular degeneration associated with age.
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