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The classification of tumors of the ovary (female gonad or) is based on the location narcissistic personality disorder from which they develop ovarian tumors themselves. A distinction is therefore: 1- tumors of the germinal epithelium (or surface epithelium or coelomic). narcissistic personality disorder These tumors are generated epithelium that covers the outside of the ovary. They constitute the majority of ovarian cancers. 2- Germ cell tumors, narcissistic personality disorder which arise from the germ cell which is inside the ovary. Under normal conditions, the germ cell will give rise to the oocyte, but genetic modifications and / or under different stimuli, can differentiate into germ cell tumor effect. These tumors account for approximately 20% of all cancers are more common in girls and young women. 3- of sex cord stromal tumors: these derive from specialized cells of the ovary, or stromal cells, which support function of germ cells and endocrine activity (ie producing hormones). Not all tumors derived from these cells produce hormones, however. The ovary also may be the site of metastasis of cancer from other organs.
ETIOLOGY 1- Genetic factors: in 5-13% of cases has been recognized a genetic predisposition. In particular, if a person in the family has been suffering from ovarian cancer, the risk of developing a blood relation increases narcissistic personality disorder by about 3.6 times the normal risk. The genes whose mutations predispose to ovarian cancer are: BRCA1 (90% of cases) and BRCA 2 (10% of cases). In families expressing mutations narcissistic personality disorder of these genes, there is a 50% risk of developing ovarian cancer by age 70; in the general population (subjects who do not have mutations in genes) narcissistic personality disorder the risk is 1.8%. Other genes involved are the p53 (which is a tumor suppressor and is mutated when no longer able to control cancer cells) and K-ras (which instead is an oncogene, and then when it is activated predisposes to the development of tumors). narcissistic personality disorder There are three syndromes of ovarian cancer family: - Breast and ovarian cancer syndrome: ovarian cancer associated with breast cancer. People with this syndrome have increased risk of developing breast and ovarian cancer than the general population. narcissistic personality disorder This syndrome is 65-75% of cases of hereditary ovarian cancer; - Hereditary non-polyposis colorectal cancer syndrome: ovarian cancer associated with colorectal cancer and endometrial. This syndrome is 10-15% of cases of hereditary ovarian cancer and is associated narcissistic personality disorder with mutations in the genes MLH1 and MSH2; - Site-specific ovarian cancer narcissistic personality disorder syndrome, narcissistic personality disorder which constitutes 10-15% of cases of hereditary ovarian cancer. 2- Gender: Women who have never been pregnant are at increased risk of ovarian cancer narcissistic personality disorder and the number of pregnancies is inversely related to the risk of cancer. The early menarche and late menopause (which increase narcissistic personality disorder the exposure to ovarian hormones) are directly related to an increased risk of cancer. 3- Hormonal: Drugs that induce ovulation, used in the treatment of infertility, may increase the risk of developing ovarian cancer because they act on germ cells to induce ovulation. Oral contraceptives and multiple pregnancies, rather than inhibit ovulation, decrease this risk. 4- Diet: a diet very high in saturated fat and alcohol and low in fruits and vegetables was associated with an increased risk of developing ovarian cancer.
Tumors of the germinal epithelium germinal epithelium tumors are divided into benign, borderline, and malignant and account for 60%, 5% and 35% of epithelial tumors of the ovary. The borderline tumors are tumors that have characteristics intermediate between narcissistic personality disorder benign and malignant and have a better prognosis of malignant counterpart. These tumors are further divided into serous, mucinous, endometrioid and rare forms (clear cell tumor and tumor Brenner). Serous cystadenoma This benign neoplasm narcissistic personality disorder comprising 50% of all serous tumors and is almost always confined to one ovary (unilateral); is bilateral (involving both ovaries) in 20% of cases. If the tumor is cystic defined precisely cystadenoma; if there is only the stromal component is defined adenofibroma; if there is stroma and glands
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